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Adaptive Evolution That Requires Multiple Spontaneous Mutations. I. Mutations Involving an Insertion Sequence
Escherichia coli K12 strain χ342LD requires two mutations in the bgl (β-glucosidase) operon, bglR(0) -> bglR(+) and excision of IS103 from within bglF, in order to utilize salicin. In growing cells the two mutations occur at rates of 4 X 10(-8) per cell division and <2 X 10(-12) per cell divis...
Bewaard in:
| Hoofdauteur: | |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
1988
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1203581/ https://ncbi.nlm.nih.gov/pubmed/2852143 |
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