Adaptive mutations in Escherichia coli as a model for the multiple mutational origins of tumors.
The cells in most tumors are found to carry multiple mutations; however, based upon mutation rates determined by fluctuation tests, the frequency of such multiple mutations should be so low that tumors are never detected within human populations. Fluctuation tests, which determine the cell-division-...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41758/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7777567/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.12.5669 |
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