Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney

TLRs are conserved pattern recognition receptors that detect motifs of pathogens and host material released during injury. For unknown reasons, renal TLR2 mRNA is mainly expressed by tubular cells and is enhanced upon renal ischemia/reperfusion (I/R) injury. We evaluated the role of TLR2 in I/R inju...

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Hauptverfasser: Leemans, Jaklien C., Stokman, Geurt, Claessen, Nike, Rouschop, Kasper M., Teske, Gwendoline J.D., Kirschning, Carsten J., Akira, Shizuo, van der Poll, Tom, Weening, Jan J., Florquin, Sandrine
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2005
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201659/
https://ncbi.nlm.nih.gov/pubmed/16167081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI22832
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