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Knockdown of Pu.1 by small interfering RNA in CD34(+) embryoid body cells derived from mouse ES cells turns cell fate determination to pro-B cells
The factors that regulate murine ES cell-derived hematopoietic progenitor cell (HPC) commitment to the B lymphocyte lineage remain unclear. Pu.1 plays an essential role in the development of all lymphoid lineages; however, it also regulates commitment to other blood cell lineages. In this study, we...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1201612/ https://ncbi.nlm.nih.gov/pubmed/16141339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506218102 |
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