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Knockdown of Pu.1 by small interfering RNA in CD34(+) embryoid body cells derived from mouse ES cells turns cell fate determination to pro-B cells

The factors that regulate murine ES cell-derived hematopoietic progenitor cell (HPC) commitment to the B lymphocyte lineage remain unclear. Pu.1 plays an essential role in the development of all lymphoid lineages; however, it also regulates commitment to other blood cell lineages. In this study, we...

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Detalhes bibliográficos
Main Authors: Zou, Gang-Ming, Chen, Jian-Jun, Yoder, Mervin C., Wu, Wei, Rowley, Janet D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201612/
https://ncbi.nlm.nih.gov/pubmed/16141339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506218102
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