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Non-cell-autonomous induction of tissue overgrowth by JNK/Ras cooperation in a Drosophila tumor model

The role of c-Jun N-terminal kinase (JNK) signaling in cancer is enigmatic, and both tumor-promoting and tumor-suppressing functions have been ascribed to JNK pathway components. We have used the Drosophila eye to investigate the function of the JNK pathway in three different tumor models of increas...

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Библиографические подробности
Главные авторы: Uhlirova, Mirka, Jasper, Heinrich, Bohmann, Dirk
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2005
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201591/
https://ncbi.nlm.nih.gov/pubmed/16150723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504170102
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