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An integrative model of the cardiac ventricular myocyte incorporating local control of Ca2+ release.

The local control theory of excitation-contraction (EC) coupling in cardiac muscle asserts that L-type Ca(2+) current tightly controls Ca(2+) release from the sarcoplasmic reticulum (SR) via local interaction of closely apposed L-type Ca(2+) channels (LCCs) and ryanodine receptors (RyRs). These loca...

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Bibliografiska uppgifter
Huvudupphovsmän: Greenstein, Joseph L, Winslow, Raimond L
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2002
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201479/
https://ncbi.nlm.nih.gov/pubmed/12496068
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