A Simplified Local Control Model of Calcium-Induced Calcium Release in Cardiac Ventricular Myocytes

Calcium (Ca(2+))-induced Ca(2+) release (CICR) in cardiac myocytes exhibits high gain and is graded. These properties result from local control of Ca(2+) release. Existing local control models of Ca(2+) release in which interactions between L-Type Ca(2+) channels (LCCs) and ryanodine-sensitive Ca(2+...

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Bibliographic Details
Main Authors: Hinch, R., Greenstein, J. L., Tanskanen, A. J., Xu, L., Winslow, R. L.
Format: Artigo
Language:Inglês
Published: Biophysical Society 2004
Subjects:
Biophysical Theory and Modeling
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304886/
https://ncbi.nlm.nih.gov/pubmed/15465866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.049973
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