NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia

The myelodysplastic syndromes (MDSs) are a group of clonal hematopoietic stem-cell disorders characterized by ineffective hematopoiesis and dysplasia. A wide spectrum of genetic aberrations has been associated with MDS, including chromosomal translocations involving the NUP98 gene. Using a NUP98-HOX...

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Bibliografiske detaljer
Main Authors: Lin, Ying-Wei, Slape, Christopher, Zhang, Zhenhua, Aplan, Peter D.
Format: Artigo
Sprog:Inglês
Udgivet: © 2005 by The American Society of Hematology 2005
Fag:
Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201424/
https://ncbi.nlm.nih.gov/pubmed/15755899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-12-4794
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