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NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia
The myelodysplastic syndromes (MDSs) are a group of clonal hematopoietic stem-cell disorders characterized by ineffective hematopoiesis and dysplasia. A wide spectrum of genetic aberrations has been associated with MDS, including chromosomal translocations involving the NUP98 gene. Using a NUP98-HOX...
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| Formaat: | Artigo |
| Taal: | Inglês |
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© 2005 by The American Society of Hematology
2005
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1201424/ https://ncbi.nlm.nih.gov/pubmed/15755899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-12-4794 |
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