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Fhl2 deficiency results in osteopenia due to decreased activity of osteoblasts

Osteoporosis is one of the major health problems today, yet little is known about the loss of bone mass caused by reduced activity of the bone-forming osteoblasts. Here we show that mice deficient for the transcriptional cofactor four and a half LIM domains 2 (Fhl2) exhibit a dramatic decrease of bo...

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Detalhes bibliográficos
Main Authors: Günther, Thomas, Poli, Cecilia, Müller, Judith M, Catala-Lehnen, Philip, Schinke, Thorsten, Yin, Na, Vomstein, Sandra, Amling, Michael, Schüle, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201354/
https://ncbi.nlm.nih.gov/pubmed/16079911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600773
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