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Fhl2 deficiency results in osteopenia due to decreased activity of osteoblasts

Osteoporosis is one of the major health problems today, yet little is known about the loss of bone mass caused by reduced activity of the bone-forming osteoblasts. Here we show that mice deficient for the transcriptional cofactor four and a half LIM domains 2 (Fhl2) exhibit a dramatic decrease of bo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Günther, Thomas, Poli, Cecilia, Müller, Judith M, Catala-Lehnen, Philip, Schinke, Thorsten, Yin, Na, Vomstein, Sandra, Amling, Michael, Schüle, Roland
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201354/
https://ncbi.nlm.nih.gov/pubmed/16079911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600773
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