Intranasal Delivery of Group B Meningococcal Native Outer Membrane Vesicle Vaccine Induces Local Mucosal and Serum Bactericidal Antibody Responses in Rabbits

We have previously shown that intranasal immunization of mice with meningococcal native outer membrane vesicles (NOMV) induces both a good local mucosal antibody response and a good systemic bactericidal antibody response. However, in the intranasal mouse model, some of the NOMV entered the lung and...

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Autori principali: Shoemaker, David R., Saunders, Nancy B., Brandt, Brenda L., Moran, E. Ellen, LaClair, Andrew D., Zollinger, Wendell D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
Soggetti:
Microbial Immunity and Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201206/
https://ncbi.nlm.nih.gov/pubmed/16041018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.8.5031-5038.2005
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