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Intranasal Delivery of Group B Meningococcal Native Outer Membrane Vesicle Vaccine Induces Local Mucosal and Serum Bactericidal Antibody Responses in Rabbits

We have previously shown that intranasal immunization of mice with meningococcal native outer membrane vesicles (NOMV) induces both a good local mucosal antibody response and a good systemic bactericidal antibody response. However, in the intranasal mouse model, some of the NOMV entered the lung and...

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Autors principals: Shoemaker, David R., Saunders, Nancy B., Brandt, Brenda L., Moran, E. Ellen, LaClair, Andrew D., Zollinger, Wendell D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201206/
https://ncbi.nlm.nih.gov/pubmed/16041018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.8.5031-5038.2005
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