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Repeated high doses of avermectins cause prolonged sterilisation, but do not kill, Onchocerca ochengi adult worms in African cattle

BACKGROUND: Ivermectin (Mectizan™, Merck and CO. Inc.) is being widely used in the control of human onchocerciasis (Onchoverca volvulus) because of its potent effect on microfilariae. Human studies have suggested that, at the standard dose of 150 μg/kg an annual treatment schedule of ivermectin reve...

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Главные авторы: deC Bronsvoort, Barend M, Renz, Alfons, Tchakouté, Virginia, Tanya, Vincent N, Ekale, David, Trees, Alexander J
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2005
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1200428/
https://ncbi.nlm.nih.gov/pubmed/16086838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2883-4-8
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