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Repeated high doses of avermectins cause prolonged sterilisation, but do not kill, Onchocerca ochengi adult worms in African cattle

BACKGROUND: Ivermectin (Mectizan™, Merck and CO. Inc.) is being widely used in the control of human onchocerciasis (Onchoverca volvulus) because of its potent effect on microfilariae. Human studies have suggested that, at the standard dose of 150 μg/kg an annual treatment schedule of ivermectin reve...

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Bibliografiske detaljer
Main Authors: deC Bronsvoort, Barend M, Renz, Alfons, Tchakouté, Virginia, Tanya, Vincent N, Ekale, David, Trees, Alexander J
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1200428/
https://ncbi.nlm.nih.gov/pubmed/16086838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2883-4-8
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