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Biological function of the vaccinia virus Z-DNA-binding protein E3L: Gene transactivation and antiapoptotic activity in HeLa cells
The vaccinia virus (VV) E3L protein is essential for virulence and has anti-apoptotic activity. In mice, Z-DNA-binding activity of the N-terminal domain of E3L (Zα) is necessary for viral lethality. Here, we report that inhibition of hygromycin-B-induced apoptosis in HeLa cells depends on Z-DNA bind...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2005
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1200295/ https://ncbi.nlm.nih.gov/pubmed/16126896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506011102 |
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