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Direct recognition by αβ cytolytic T cells of Hfe, a MHC class Ib molecule without antigen-presenting function
Crystallographic analysis of human Hfe has documented an overall structure similar to classical (class Ia) MHC molecules with a peptide binding groove deprived of ligand. Thus, to address the question of whether αβ T cells could recognize MHC molecules independently of bound ligands, we studied huma...
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| Autors principals: | , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1200262/ https://ncbi.nlm.nih.gov/pubmed/16123136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502309102 |
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