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Human small intestinal mucosa harbours a small population of cytolytically active CD8(+) αβ T lymphocytes

Intraepithelial lymphocytes (IEL) in normal human small intestine exhibit cytotoxicity. This study was undertaken to characterize the effector cells and their mode of action. Freshly isolated jejunal IEL and lamina propria lymphocytes (LPL), as well as IEL and LPL depleted of CD4(+), CD8(+) and T-ce...

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Bibliographic Details
Main Authors: Melgar, Silvia, Bas, Anna, Hammarström, Sten, Hammarström, Marie-Louise
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782753/
https://ncbi.nlm.nih.gov/pubmed/12153510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2002.01461.x
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