Direct recognition by αβ cytolytic T cells of Hfe, a MHC class Ib molecule without antigen-presenting function

Crystallographic analysis of human Hfe has documented an overall structure similar to classical (class Ia) MHC molecules with a peptide binding groove deprived of ligand. Thus, to address the question of whether αβ T cells could recognize MHC molecules independently of bound ligands, we studied huma...

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Bibliografische gegevens
Hoofdauteurs: Rohrlich, Pierre S., Fazilleau, Nicolas, Ginhoux, Florent, Firat, Hüseyin, Michel, Frédérique, Cochet, Madeleine, Laham, Nihay, Roth, Marie Paule, Pascolo, Steve, Nato, Faridabano, Coppin, Hélène, Charneau, Pierre, Danos, Olivier, Acuto, Oreste, Ehrlich, Rachel, Kanellopoulos, Jean, Lemonnier, François A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2005
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1200262/
https://ncbi.nlm.nih.gov/pubmed/16123136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502309102
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