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Binding and repression of translation of the cognate mRNA by Trichinella spiralis thymidylate synthase differ from the corresponding interactions of the human enzyme

Thymidylate synthase (TS) of Trichinella spiralis, a parasitic nematode causing trichinellosis, was found to bind its own mRNA and repress translation of the latter, similar to its human counter-part [Chu, Koeller, Casey, Drake, Chabner, Elwood, Zinn and Allegra (1991) Proc. Natl. Acad. Sci. U.S.A....

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Detalhes bibliográficos
Main Authors: Cieśla, Joanna, Jagielska, Elżbieta, Skopiński, Tomasz, Dąbrowska, Magdalena, Maley, Frank, Rode, Wojciech
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1199661/
https://ncbi.nlm.nih.gov/pubmed/15882146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050548
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