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Interaction between Thymidylate Synthase and Its Cognate mRNA in Zebrafish Embryos

Thymidylate synthase (TS), which catalyzes the de novo synthesis of dUMP, is an important target for cancer therapy. In this report, the effects of 5-fluorouracil (5-FU) and ZD1694 on the regulation of TS gene expression were evaluated in zebrafish embryos. Our results revealed that the expression o...

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Detalhes bibliográficos
Main Authors: Zhang, Yuyan, Yang, Shaoli, Liu, Ming, Song, Chunxia, Wu, Ning, Ling, Peixue, Chu, Edward, Lin, Xiukun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868900/
https://ncbi.nlm.nih.gov/pubmed/20485548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010618
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