Thymidylate Synthase Protein and p53 mRNA Form an In Vivo Ribonucleoprotein Complex

A thymidylate synthase (TS)-ribonucleoprotein (RNP) complex composed of TS protein and the mRNA of the tumor suppressor gene p53 was isolated from cultured human colon cancer cells. RNA gel shift assays confirmed a specific interaction between TS protein and the protein-coding region of p53 mRNA, an...

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Detalhes bibliográficos
Main Authors: Chu, Edward, Copur, Sitki M., Ju, Jingfang, Chen, Tian-men, Khleif, Samir, Voeller, Donna M., Mizunuma, Nobuyuki, Patel, Mahendra, Maley, Gladys F., Maley, Frank, Allegra, Carmen J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC116086/
https://ncbi.nlm.nih.gov/pubmed/9891091
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