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A Note on Exact Tests of Hardy-Weinberg Equilibrium

Deviations from Hardy-Weinberg equilibrium (HWE) can indicate inbreeding, population stratification, and even problems in genotyping. In samples of affected individuals, these deviations can also provide evidence for association. Tests of HWE are commonly performed using a simple χ(2) goodness-of-fi...

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Bibliografske podrobnosti
Main Authors: Wigginton, Janis E., Cutler, David J., Abecasis, Gonçalo R.
Format: Artigo
Jezik:Inglês
Izdano: The American Society of Human Genetics 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1199378/
https://ncbi.nlm.nih.gov/pubmed/15789306
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