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Exact Tests of Hardy-Weinberg Equilibrium and Homogeneity of Disequilibrium across Strata

Detecting departures from Hardy-Weinberg equilibrium (HWE) of marker-genotype frequencies is a crucial first step in almost all human genetic analyses. When a sample is stratified by multiple ethnic groups, it is important to allow the marker-allele frequencies to differ over the strata. In this sit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schaid, Daniel J. , Batzler, Anthony J. , Jenkins, Gregory D. , Hildebrandt, Michelle A. T. 
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society of Human Genetics 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698709/
https://ncbi.nlm.nih.gov/pubmed/17186465
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