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Approximate and Exact Tests of Hardy-Weinberg Equilibrium Using Uncertain Genotypes
Testing for Hardy-Weinberg equilibrium (HWE) is commonly used as a quality control filter in genome-wide scans for markers with experimentally determined genotypes. In contrast, for markers with imputed genotypes, there are post-imputation metrics of quality that can be used as screens but there are...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4141651/ https://ncbi.nlm.nih.gov/pubmed/21922537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20612 |
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