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Cloning and characterization of the human glutathione synthetase 5′-flanking region
GSH synthesis occurs through a two-step enzymatic reaction driven by GCL (glutamate–cysteine ligase; made up of catalytic and modifying subunits) and GSS (glutathione synthetase). In humans, oxidative stress regulates GCL expression in an antioxidant response element-dependent manner via Nrf2 [NFE (...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Portland Press Ltd.
2005
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1198932/ https://ncbi.nlm.nih.gov/pubmed/15890065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050439 |
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