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Cloning and characterization of the human glutathione synthetase 5′-flanking region

GSH synthesis occurs through a two-step enzymatic reaction driven by GCL (glutamate–cysteine ligase; made up of catalytic and modifying subunits) and GSS (glutathione synthetase). In humans, oxidative stress regulates GCL expression in an antioxidant response element-dependent manner via Nrf2 [NFE (...

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Detalhes bibliográficos
Main Authors: Lee, Taunia D., Yang, Heping, Whang, Janet, Lu, Shelly C.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1198932/
https://ncbi.nlm.nih.gov/pubmed/15890065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050439
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