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Development of an in vitro cleavage assay system to examine vaccinia virus I7L cysteine proteinase activity

Through the use of transient expression assays and directed genetics, the vaccinia virus (VV) I7L gene product has been implicated as the major maturational proteinase required for viral core protein cleavage to occur during virion assembly. To confirm this hypothesis and to enable a biochemical exa...

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Bibliografske podrobnosti
Main Authors: Byrd, Chelsea M, Hruby, Dennis E
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1198262/
https://ncbi.nlm.nih.gov/pubmed/16105175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-2-63
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