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Molecular Dissection of the Vaccinia Virus I7L Core Protein Proteinase

The vaccinia virus I7L gene product is predicted to be a cysteine proteinase and is demonstrated in this study to be responsible for cleavage of each of the three major core protein precursors (P4a, P4b, and P25K) in vivo. Mutagenesis of the putative catalytic triad of I7L or of the cleavage sites i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Byrd, Chelsea M., Bolken, Tove' C., Hruby, Dennis E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC225000/
https://ncbi.nlm.nih.gov/pubmed/14512576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.20.11279-11283.2003
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