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Development of an in vitro cleavage assay system to examine vaccinia virus I7L cysteine proteinase activity

Through the use of transient expression assays and directed genetics, the vaccinia virus (VV) I7L gene product has been implicated as the major maturational proteinase required for viral core protein cleavage to occur during virion assembly. To confirm this hypothesis and to enable a biochemical exa...

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Autors principals: Byrd, Chelsea M, Hruby, Dennis E
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1198262/
https://ncbi.nlm.nih.gov/pubmed/16105175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-2-63
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