Inhibition of Pkhd1 Impairs Tubulomorphogenesis of Cultured IMCD Cells

Fibrocystin/polyductin (FPC), the gene product of PKHD1, is responsible for autosomal recessive polycystic kidney disease (ARPKD). This disease is characterized by symmetrically large kidneys with ectasia of collecting ducts. In the kidney, FPC predominantly localizes to the apical domain of tubule...

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Detalhes bibliográficos
Main Authors: Mai, Weiyi, Chen, Dong, Ding, Tianbing, Kim, Ingyu, Park, Sujun, Cho, Sae-youll, Chu, Julia S.F., Liang, Dan, Wang, Ning, Wu, Dianqing, Li, Song, Zhao, Ping, Zent, Roy, Wu, Guanqing
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2005
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196347/
https://ncbi.nlm.nih.gov/pubmed/15975909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-11-1019
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