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Inhibition of Pkhd1 Impairs Tubulomorphogenesis of Cultured IMCD Cells
Fibrocystin/polyductin (FPC), the gene product of PKHD1, is responsible for autosomal recessive polycystic kidney disease (ARPKD). This disease is characterized by symmetrically large kidneys with ectasia of collecting ducts. In the kidney, FPC predominantly localizes to the apical domain of tubule...
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| Autori principali: | , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Cell Biology
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1196347/ https://ncbi.nlm.nih.gov/pubmed/15975909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-11-1019 |
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