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Genomic Approach to Identifying the Putative Target of and Mechanisms of Resistance to Mefloquine in Mycobacteria

The emergence of mycobacterial resistance to multiple antimicrobials emphasizes the need for new compounds. The antimycobacterial activity of mefloquine has been recently described. Mycobacterium avium, Mycobacterium smegmatis, and Mycobacterium tuberculosis are susceptible to mefloquine in vitro, a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Danelishvili, Lia, Wu, Martin, Young, Lowell S., Bermudez, Luiz E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1195445/
https://ncbi.nlm.nih.gov/pubmed/16127044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.9.3707-3714.2005
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