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Genomic Approach to Identifying the Putative Target of and Mechanisms of Resistance to Mefloquine in Mycobacteria

The emergence of mycobacterial resistance to multiple antimicrobials emphasizes the need for new compounds. The antimycobacterial activity of mefloquine has been recently described. Mycobacterium avium, Mycobacterium smegmatis, and Mycobacterium tuberculosis are susceptible to mefloquine in vitro, a...

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Detalhes bibliográficos
Main Authors: Danelishvili, Lia, Wu, Martin, Young, Lowell S., Bermudez, Luiz E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1195445/
https://ncbi.nlm.nih.gov/pubmed/16127044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.9.3707-3714.2005
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