Reversal of Mefloquine and Quinine Resistance in Plasmodium falciparum with NP30

Quinoline resistance in malaria is frequently compared with P-glycoprotein-mediated multidrug resistance (mdr) in mammalian cells. We have previously reported that nonylphenolethoxylates, such as NP30, are potential Plasmodium falciparum P-glycoprotein substrates and drug efflux inhibitors. We used...

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Detalhes bibliográficos
Main Authors: Ciach, Michelle, Zong, Kathleen, Kain, Kevin C., Crandall, Ian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC166084/
https://ncbi.nlm.nih.gov/pubmed/12878495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.8.2393-2396.2003
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