The effects of serum lipids on the <it>in vitro</it> activity of lumefantrine and atovaquone against <it>Plasmodium falciparum</it>
<p>Abstract</p> <p>Background</p> <p>Lumefantrine and atovaquone are highly lipophilic anti-malarial drugs. As a consequence absorption is increased when the drugs are taken together with a fatty meal, but the free fraction of active drug decreases in the presence of triglyceride-rich plasma lipopro...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2012-05-01
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| Serie: | Malaria Journal |
| Soggetti: | |
| Accesso online: | http://www.malariajournal.com/content/11/1/177 |
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