The effects of serum lipids on the <it>in vitro</it> activity of lumefantrine and atovaquone against <it>Plasmodium falciparum</it>

<p>Abstract</p> <p>Background</p> <p>Lumefantrine and atovaquone are highly lipophilic anti-malarial drugs. As a consequence absorption is increased when the drugs are taken together with a fatty meal, but the free fraction of active drug decreases in the presence of triglyceride-rich plasma lipopro...

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Detalhes bibliográficos

Principais autores:	Chotivanich Kesinee, Mungthin Mathirut, Ruengweerayuth Ronnatrai, Udomsangpetch Rachanee, Dondorp Arjen M, Singhasivanon Pratap, Pukrittayakamee Sasithon, White Nicholas J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2012-05-01
Colecção:	Malaria Journal
Assuntos:	Malaria Anti-malarial drugs <it>In vitro</it>-susceptibility
Acesso em linha:	http://www.malariajournal.com/content/11/1/177
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