Phosphorylated FADD induces NF-κB, perturbs cell cycle, and is associated with poor outcome in lung adenocarcinomas

In an effort to identify a clinical biomarker for lung cancer, we used cDNA microarray and 2D protein analyses to demonstrate that increased Fas-associated death domain (FADD) mRNA and protein were significantly associated with poor survival. Analyses of copy number and sequence of the FADD gene in...

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מידע ביבליוגרפי
Main Authors: Chen, Guoan, Bhojani, Mahaveer S., Heaford, Andrew C., Chang, Daniel C., Laxman, Bharathi, Thomas, Dafydd G., Griffin, Laura B., Yu, James, Coppola, Julia M., Giordano, Thomas J., Lin, Lin, Adams, David, Orringer, Mark B., Ross, Brian D., Beer, David G., Rehemtulla, Alnawaz
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2005
נושאים:
Biological Sciences
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1194899/
https://ncbi.nlm.nih.gov/pubmed/16109772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500397102
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