Phosphorylated FADD induces NF-κB, perturbs cell cycle, and is associated with poor outcome in lung adenocarcinomas

In an effort to identify a clinical biomarker for lung cancer, we used cDNA microarray and 2D protein analyses to demonstrate that increased Fas-associated death domain (FADD) mRNA and protein were significantly associated with poor survival. Analyses of copy number and sequence of the FADD gene in...

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Detalhes bibliográficos
Main Authors: Chen, Guoan, Bhojani, Mahaveer S., Heaford, Andrew C., Chang, Daniel C., Laxman, Bharathi, Thomas, Dafydd G., Griffin, Laura B., Yu, James, Coppola, Julia M., Giordano, Thomas J., Lin, Lin, Adams, David, Orringer, Mark B., Ross, Brian D., Beer, David G., Rehemtulla, Alnawaz
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1194899/
https://ncbi.nlm.nih.gov/pubmed/16109772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500397102
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