Phosphorylated FADD induces NF-κB, perturbs cell cycle, and is associated with poor outcome in lung adenocarcinomas

In an effort to identify a clinical biomarker for lung cancer, we used cDNA microarray and 2D protein analyses to demonstrate that increased Fas-associated death domain (FADD) mRNA and protein were significantly associated with poor survival. Analyses of copy number and sequence of the FADD gene in...

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Bibliografske podrobnosti
Main Authors: Chen, Guoan, Bhojani, Mahaveer S., Heaford, Andrew C., Chang, Daniel C., Laxman, Bharathi, Thomas, Dafydd G., Griffin, Laura B., Yu, James, Coppola, Julia M., Giordano, Thomas J., Lin, Lin, Adams, David, Orringer, Mark B., Ross, Brian D., Beer, David G., Rehemtulla, Alnawaz
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2005
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1194899/
https://ncbi.nlm.nih.gov/pubmed/16109772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500397102
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