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Indomethacin-Induced Apoptosis in Esophageal Adenocarcinoma Cells Involves Upregulation of Bax and Translocation of Mitochondrial Cytochrome C Independent of COX-2 Expression

The prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs) has been shown to exert a chemopreventive effect in esophageal and other gastrointestinal tumors. The precise mechanism by which this occurs, however, is unknown. While the inhibition of COX-2 as a potential explanation for this chem...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Aggarwal, Sanjeev, Taneja, Neelam, Lin, Lin, Orringer, Mark B, Rehemtulla, Alnawaz, Beer, David G
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature America, Inc. 2000
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1550298/
https://ncbi.nlm.nih.gov/pubmed/11005569
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