Large-Scale Analysis of Adeno-Associated Virus Vector Integration Sites in Normal Human Cells

The integration sites of viral vectors used in human gene therapy can have important consequences for safety and efficacy. However, an extensive evaluation of adeno-associated virus (AAV) vector integration sites has not been completed, despite the ongoing use of AAV vectors in clinical trials. Here...

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Bibliografiske detaljer
Main Authors: Miller, Daniel G., Trobridge, Grant D., Petek, Lisa M., Jacobs, Michael A., Kaul, Rajinder, Russell, David W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Gene Delivery
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1193581/
https://ncbi.nlm.nih.gov/pubmed/16103194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.17.11434-11442.2005
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