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Large-Scale Analysis of Adeno-Associated Virus Vector Integration Sites in Normal Human Cells

The integration sites of viral vectors used in human gene therapy can have important consequences for safety and efficacy. However, an extensive evaluation of adeno-associated virus (AAV) vector integration sites has not been completed, despite the ongoing use of AAV vectors in clinical trials. Here...

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Detalhes bibliográficos
Main Authors: Miller, Daniel G., Trobridge, Grant D., Petek, Lisa M., Jacobs, Michael A., Kaul, Rajinder, Russell, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1193581/
https://ncbi.nlm.nih.gov/pubmed/16103194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.17.11434-11442.2005
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