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Curing of yeast [PSI(+)] prion by guanidine inactivation of Hsp104 does not require cell division

Propagation of the yeast prion [PSI(+)], a self-replicating aggregated form of Sup35p, requires Hsp104. One model to explain this phenomenon proposes that, in the absence of Hsp104, Sup35p aggregates enlarge but fail to replicate thus becoming diluted out as the yeast divide. To test this model, we...

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Detaylı Bibliyografya
Asıl Yazarlar: Wu, Yue-Xuan, Greene, Lois E., Masison, Daniel C., Eisenberg, Evan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1192827/
https://ncbi.nlm.nih.gov/pubmed/16123122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506384102
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