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Curing of yeast [PSI(+)] prion by guanidine inactivation of Hsp104 does not require cell division
Propagation of the yeast prion [PSI(+)], a self-replicating aggregated form of Sup35p, requires Hsp104. One model to explain this phenomenon proposes that, in the absence of Hsp104, Sup35p aggregates enlarge but fail to replicate thus becoming diluted out as the yeast divide. To test this model, we...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1192827/ https://ncbi.nlm.nih.gov/pubmed/16123122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506384102 |
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