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Endothelial cell injury by high glucose and heparanase is prevented by insulin, heparin and basic fibroblast growth factor
BACKGROUND: Uncontrolled hyperglycemia is the main risk factor in the development of diabetic vascular complications. The endothelial cells are the first cells targeted by hyperglycemia. The mechanism of endothelial injury by high glucose is still poorly understood. Heparanase production, induced by...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1192813/ https://ncbi.nlm.nih.gov/pubmed/16086844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-4-12 |
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