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Endothelial cell injury by high glucose and heparanase is prevented by insulin, heparin and basic fibroblast growth factor

BACKGROUND: Uncontrolled hyperglycemia is the main risk factor in the development of diabetic vascular complications. The endothelial cells are the first cells targeted by hyperglycemia. The mechanism of endothelial injury by high glucose is still poorly understood. Heparanase production, induced by...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Han, Juying, Mandal, Anil K, Hiebert, Linda M
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2005
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1192813/
https://ncbi.nlm.nih.gov/pubmed/16086844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-4-12
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