Transfection of the type II TGF-beta receptor into colon cancer cells increases receptor expression, inhibits cell growth, and reduces the malignant phenotype.

OBJECTIVE: To determine if transfection of SW48 colon cancer cells with the type II transforming growth factor-beta (TGF-beta) receptor restores growth inhibition and reverses the in vitro and in vivo malignant phenotype. SUMMARY BACKGROUND DATA: The authors have previously shown that SW48 colon can...

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Detalhes bibliográficos
Main Authors: MacKay, S L, Auffenberg, T, Tannahill, C L, Ksontini, R, Josephs, M D, Nowak, M, Moldawer, L L, Copeland, E M
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1191376/
https://ncbi.nlm.nih.gov/pubmed/9637541
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