Colon cancer cells that are not growth inhibited by TGF-beta lack functional type I and type II TGF-beta receptors.

OBJECTIVE: The authors determined the molecular mechanisms for the failure of transforming growth factor-beta (TGF-beta) to inhibit the growth of SW1116 and SW48 colon cancer cell lines. BACKGROUND: Transforming growth factor-beta is a bifunctional regulator of cell growth that typically stimulates...

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Detalhes bibliográficos
Main Authors: MacKay, S L, Yaswen, L R, Tarnuzzer, R W, Moldawer, L L, Bland, K I, Copeland, E M, Schultz, G S
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1234710/
https://ncbi.nlm.nih.gov/pubmed/7794080
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