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Reconstitution and transphosphorylation of TGF-beta receptor complexes.

Transforming growth factor-beta (TGF-beta) signals by contacting two distantly related transmembrane serine/threonine kinases called receptors I (T beta R-I) and II (T beta R-II). TGF-beta binds to T beta R-II, which is a constitutively active kinase and this complex recruits T beta R-I, causing its...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ventura, F, Doody, J, Liu, F, Wrana, J L, Massagué, J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC395521/
https://ncbi.nlm.nih.gov/pubmed/7988555
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