The Fission Yeast Crb2/Chk1 Pathway Coordinates the DNA Damage and Spindle Checkpoint in Response to Replication Stress Induced by Topoisomerase I Inhibitor

Living organisms experience constant threats that challenge their genome stability. The DNA damage checkpoint pathway coordinates cell cycle progression with DNA repair when DNA is damaged, thus ensuring faithful transmission of the genome. The spindle assembly checkpoint inhibits chromosome segrega...

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Detalhes bibliográficos
Main Authors: Collura, Ada, Blaisonneau, Joel, Baldacci, Giuseppe, Francesconi, Stefania
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Chromosome Structure and Dynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190313/
https://ncbi.nlm.nih.gov/pubmed/16107732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.17.7889-7899.2005
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