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The Fission Yeast Crb2/Chk1 Pathway Coordinates the DNA Damage and Spindle Checkpoint in Response to Replication Stress Induced by Topoisomerase I Inhibitor

Living organisms experience constant threats that challenge their genome stability. The DNA damage checkpoint pathway coordinates cell cycle progression with DNA repair when DNA is damaged, thus ensuring faithful transmission of the genome. The spindle assembly checkpoint inhibits chromosome segrega...

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Hlavní autoři: Collura, Ada, Blaisonneau, Joel, Baldacci, Giuseppe, Francesconi, Stefania
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190313/
https://ncbi.nlm.nih.gov/pubmed/16107732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.17.7889-7899.2005
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