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The Fission Yeast Crb2/Chk1 Pathway Coordinates the DNA Damage and Spindle Checkpoint in Response to Replication Stress Induced by Topoisomerase I Inhibitor

Living organisms experience constant threats that challenge their genome stability. The DNA damage checkpoint pathway coordinates cell cycle progression with DNA repair when DNA is damaged, thus ensuring faithful transmission of the genome. The spindle assembly checkpoint inhibits chromosome segrega...

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Bibliografiske detaljer
Main Authors: Collura, Ada, Blaisonneau, Joel, Baldacci, Giuseppe, Francesconi, Stefania
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190313/
https://ncbi.nlm.nih.gov/pubmed/16107732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.17.7889-7899.2005
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